

In the world of medicine and treatment, we sometimes hear about something strange called "placebo" or "dummy treatment." But what exactly is it? Simply put, it's a treatment that doesn't contain any active medical ingredients, yet it is given to the patient as if it were a real medicine. The surprising part is that many people feel better after taking the placebo, even though it contains no medical components. How does this happen? The answer lies in the power of the mind and the effect of expectations. we will explore the impact of the placebo effect and how it improves a patient's health through its psychological influence, even though it is not an actual treatment.
What is Placebo or Dummy Treatment?
Placebo is a treatment that contains no active medical ingredients but is given to the patient as if it were a real medicine. Placebo is used in clinical research to determine the effectiveness of other drugs and treatments. Although placebo has no actual therapeutic effect, it can improve the patient's condition due to the psychological effect of the belief that they are taking an effective treatment.
How Does Placebo Work? Placebo works through the "illusion effect" or "psychological effect." This means that when a patient believes that the treatment they are taking will help or cure them, they begin to feel better, whether this is the result of the actual treatment or the power of their mind and expectations.
Effectiveness of Placebo Treatment Placebo has proven effective in many cases such as pain, depression, anxiety, and some psychological disorders. Often, the belief that a person is taking real medicine helps them feel better even if there is no actual treatment. Placebo can also be effective in some difficult medical conditions, as it helps the patient feel improvement without real treatment. However, not everyone responds to placebo in the same way. Its effectiveness largely depends on the individual and their psychological response to the placebo treatment.
Components of Placebo Since placebo is essentially a dummy treatment, its actual components vary depending on the type of placebo and how it is prepared. Because it is not a real medicine and contains no active ingredients, these components are usually inactive substances. Here are some components that placebo may contain:
Sugars (such as sucrose or glucose)
Description: Some types of placebo are made using simple sugars like sucrose or glucose. These substances are often in the form of tablets or capsules.
Ingredients: Sucrose, glucose, or other sweet substances.
Purpose: They give the feeling that the patient is taking real medicine and are used in oral medications.
Starch
Description: Starch is an inactive substance that can be used in the production of placebo pills. It has no therapeutic effect but improves the appearance and texture of the pills or tablets.
Ingredients: Corn starch or potato starch.
Purpose: It makes the pills or tablets look like effective medicine.
Water or Inactive Liquids
Description: Some placebo treatments come in liquid form, such as water-based solutions or saline solutions, which contain inactive substances and are often used to relieve discomfort in certain situations.
Ingredients: Distilled water or saline solution (such as low-concentration sodium chloride solution).
Purpose: It gives the feeling of treatment without having any actual effect on the health condition.
Colors and Additives
Description: Some placebo may contain additives such as colors or preservatives. These substances do not affect healing but make the placebo resemble real medicine.
Ingredients: Food dyes or preservatives like metabisulfite or sodium benzoate.
Purpose: To improve the appearance and texture of the placebo so that it looks like actual medicine.
Gelatin
Description: In the case of gelatin capsules or pills, gelatin is used as the container for the inactive substance, which is the placebo.
Ingredients: Gelatin (derived from animals or plants).
Purpose: To form capsules that look like real medicines.
Salt or Sodium
Description: Some placebo treatments contain salt or sodium, especially if the placebo is in liquid or solution form.
Ingredients: Sodium chloride or other sodium-containing substances.
Purpose: To help prepare solutions or placebo herbal remedies.
Fats or Oils
Description: In some cases, vegetable fats or oils may be used in the preparation of placebo, especially in ointments or fatty preparations.
Ingredients: Almond oil, olive oil, or other vegetable oils.
Purpose: To help manufacture ointments or creams that may be used on the skin.
Inactive Vitamins and Minerals
Description: Sometimes placebo contains vitamins or minerals, but the concentration is not enough to have a real therapeutic effect.
Ingredients: Vitamins like Vitamin C, Vitamin B12, or minerals like magnesium.
Purpose: To give the person the feeling that they are taking real supplements even though the concentration is not sufficient for actual effect.
Fragrances and Scented Substances
Description: Placebo sometimes contains fragrances or substances that make it smell like real medicine.
Ingredients: Essential oils such as lavender oil or lemon oil.
Purpose: To enhance the sensory experience of the patient and make the placebo appear as if it is real treatment.
Plant Components or Herbs
Description: Some placebo treatments may contain plant-based ingredients or herbs, but these do not have a real therapeutic effect.
Ingredients: Herbs like mint or chamomile.
Purpose: To create a psychological effect using plant materials without any actual therapeutic effect.
Types of Placebo
Placebo can take various forms and can be used in different ways, with each type depending on the method or the condition it is applied to. Here are the different types:
Medicinal Placebo (Fake Medicine)
This is the most well-known type of placebo and includes pills, liquids, or any form of treatment intended to help with a particular health issue. However, there are no active ingredients in this treatment, but the person taking it believes it will help.
Example: If a person has a headache and is given a placebo pill, they won't improve because of the active ingredient, but because they believe it will help, their brain releases chemicals like endorphins, leading to improvement.
Procedural Placebo (Fake Procedure)
In this type, a medical or surgical procedure is performed that has no real effect on the body, but the patient believes it will help.
Example: If a patient undergoes a sham surgery (like a scope procedure with no actual surgical intervention), they might feel better simply because they believe the procedure will help.
Psychological Placebo (Fake Psychological Treatment)
This type relies on psychological techniques like relaxation or cognitive behavioral therapy, where the individual is led to believe that the psychological treatment is the reason for their improvement.
Example: If a person experiences anxiety and uses a relaxation technique or listens to soothing music with the expectation of improvement, they may feel mentally better.
Social Placebo
In this type, the placebo takes the form of support from others, such as doctors or friends, who make the person feel they will improve or that the treatment will help, even if there is no real treatment.
Example: If a person has a health issue and sees a doctor who provides emotional support, they might believe that this support is the reason for their improvement.
Placebo Through Affirmations
In this type, the person is given positive words or phrases that encourage them and make them believe that the treatment or guidance will help. This leads them to believe the treatment will be effective because they hear positive reinforcement.
Example: If a person has pain and the doctor says, "You will feel better soon," just hearing this might make the person feel better, leading to a reduction in pain.
Negative Placebo
This is a rare type of placebo where the person is told that the treatment won’t work or that they won’t improve, and the body responds in the opposite way, reducing pain or improving the health condition.
Example: If a person has a headache and is told "this treatment won’t do anything," their brain might do the opposite and improve the condition due to psychological factors.
Genetic Placebo
This type relies on the belief in genetic factors. The person believes that their health condition will improve because their genes are "compatible" with the treatment or placebo.
Example: If a person believes that their body is able to heal because of certain genetic traits, this belief can enhance the placebo effect.
Placebo in Alternative Medicine
People sometimes use alternative treatments like herbs, energy healing, or acupuncture, which can function as a placebo if the person believes these treatments will help, even if there is no scientific evidence to support their effectiveness.
How Placebo Works
Placebo works through a combination of psychological and neurological mechanisms:
Expectations and Beliefs
When a person believes that the treatment they are taking will help alleviate their symptoms or improve their condition, the brain begins to respond to this expectation. The belief that the "treatment" is effective stimulates the brain to release natural chemicals such as endorphins and dopamine, which help reduce pain and improve mood.
Example: If a person takes a pill and believes it will improve their health, their brain may release these chemicals, leading to a sense of improvement.
Neurological Effect
Placebo can activate areas of the brain that are involved in pain processing, such as the frontal cortex and thalamus, which can lead to pain relief or an overall improvement in mood.
In many studies, the neural activity in the brains of people who take placebo treatments has been measured, and it was found that the brain responds similarly to how it would if a person took a painkiller.
Pain Interaction
Placebo can help reduce pain by affecting the neural signaling system in the brain. This means that pain can decrease simply because the brain believes the treatment will work, thus reducing the sensation of pain.
Example: If a person has a headache and takes a placebo pill (which is actually just a fake pill), the brain may believe the treatment is effective and activate pain-relieving processes.
Social Effect
Support from a doctor or confidence in the person prescribing the treatment increases the placebo effect. When a person takes the treatment from a professional, they feel hopeful and trusting, which enhances the placebo effect.
Sometimes, positive affirmations from a doctor like "This treatment will help you feel better" can make the person feel better.
Adaptation and Repetition
With repeated use of placebo, a person may become more susceptible to its effects because they begin to associate the treatment with improvements in their condition. This connection between the treatment (even if it's fake) and symptom improvement grows stronger over time.
Self-Motivation and Mental Impact
The placebo effect is not just due to the fake medicine but also because of inner belief. When a person feels they have a chance to improve, their mind begins to guide the body towards self-healing.
The mind can stimulate natural healing processes in the body, such as boosting the immune system and improving other bodily functions.
Symptoms Resulting from Placebo Effect
Pain Improvement
Placebo can help reduce pain, whether it’s physical pain like headaches or chronic pain like backaches.
Reason: The brain assumes the treatment will be effective, so it starts releasing chemicals like endorphins (the hormones responsible for comfort and pain relief), which helps relieve pain.
Example: If a person has a headache and takes a placebo pill, the brain might start reducing the sensation of pain as if it were treating the headache naturally.
Mood Improvement
People who are affected by the placebo effect may experience an uplift in spirits or an improvement in their general mood.
Reason: Positive expectations and encouragement from those around them (like doctors or friends) lead to an increase in the release of dopamine (the happiness hormone), which improves mood.
Example: If a person has mild depression and begins taking a placebo treatment, they may notice an improvement in their mental state due to trust in the treatment.
Improvement in Psychological Symptoms (Anxiety and Stress)
Placebo can help reduce symptoms of anxiety and stress due to the sense of improvement driven by positive expectations.
Reason: The belief that the treatment will fix the psychological issue stimulates the nervous system to relax and calm negative emotions.
Example: A person feeling excessive anxiety about a specific issue may take a placebo treatment and notice that they feel calmer and less stressed.
Improvement in Physical Performance
Placebo can make a person feel more energetic or capable of engaging in physical exercise or other physical activities.
Reason: Positive expectations about physical improvement stimulate the body to function more efficiently, especially in sports or activities that require physical effort.
Example: If a person takes a placebo for muscle fatigue, they might feel an increase in energy and activity due to the influence of expectations on the body.
Improvement in Digestive Function
Placebo can help improve symptoms related to the digestive system, such as nausea or constipation.
Reason: The mind reacts to the expectation that the treatment will work on digestive symptoms, and the body begins to respond as if the treatment is effective.
Example: If someone experiences nausea or digestive issues and takes a placebo, they might notice improvement in symptoms due to the mind’s response.
Improvement in Chronic Illness Symptoms
Placebo can sometimes alleviate symptoms associated with chronic conditions like joint pain or skin diseases.
Reason: People with chronic illnesses often believe the treatment will help, and thus feel better even if the treatment isn’t effective.
Example: A person with arthritis who takes a placebo may feel less pain or experience improved mobility.
Improvement in Sleep
Placebo can help improve sleep quality or treat insomnia indirectly.
Reason: The expectation that the treatment will help with sleep leads to a positive psychological response, which helps the brain release hormones responsible for relaxation and sleep.
Example: If a person has trouble sleeping and takes a placebo (such as a fake sleeping pill), they might experience improved sleep due to the mental impact on the body.
Improvement in Overall Health
In some cases, people taking placebo may feel their general health is improving even if there is no real treatment.
Reason: Positive expectations and trust in the treatment help improve the general state of the body.
Example: A person who feels generally fatigued may feel more energized or notice an overall improvement in their health after taking a placebo.
Increased Immune Function
Placebo can stimulate the body to strengthen the immune system, leading to increased natural production of antibodies.
Reason: Positive expectations can enhance immune responses by activating hormones associated with the immune system.
Example: A person taking a placebo may feel that their immune system is stronger, leading to fewer illnesses.
Although the placebo effect can be beneficial in some cases, it also comes with certain harms and disadvantages that need to be considered. These harms vary depending on the context in which the placebo is used and the patient's condition. Let me explain the potential harms:
Masking Real Health Problems
Description: The placebo effect may make a person feel temporarily better, but in reality, they might have an underlying health issue that is not being treated properly. Sometimes, a person feels better due to the placebo, but the real problem is still there.
Harms: Delay in diagnosis and actual treatment of real health problems, such as tumors or chronic diseases.
Example: A person with a heart condition takes a placebo and feels better, but the underlying health problem remains.
Addiction to Placebo Medications or Treatments
Description: If the placebo is used repeatedly, the person might start depending on it and feel they need the placebo to feel better, even though there is no real treatment.
Harms: Dependence on the placebo instead of seeking real treatment, reducing the motivation to take effective medications or treatments.
Example: A person suffering from chronic pain uses a placebo to alleviate the pain instead of seeking real treatments like physical therapy or appropriate medications.
Deception and Loss of Trust in Medical Treatment
Description: Using a placebo may make the patient feel deceived, as the treatment they are receiving is not real. This could impact the patient's trust in doctors and medical treatments in the future.
Harms: It may cause a lack of trust between the patient and doctor or in medical treatments in general.
Example: If a patient later discovers they took a placebo instead of a real treatment, they might lose trust in doctors or medical treatments overall.
Increase in Psychological Symptoms
Description: Sometimes, the placebo effect can have the opposite effect and increase anxiety or depression instead of alleviating psychological symptoms.
Harms: Negative expectations or anxiety from the placebo effect may worsen the mental condition rather than improving it.
Example: A person suffering from anxiety takes a placebo but believes it is ineffective, which leads to worsening of negative feelings.
Masking Physical Symptoms
Description: If a patient feels better because of the placebo, they may overlook serious symptoms that need immediate attention, such as swelling or bleeding that may indicate an emergency health issue.
Harms: Delay in diagnosis and treatment, potentially leading to worsened health.
Example: A person experiencing severe fatigue or sudden weight loss relies on a placebo, delaying the search for the correct treatment.
Negative Psychological Effects on the Patient
Description: If the patient later discovers that they received a placebo, they might feel disappointed or betrayed.
Harms: This can lead to negative feelings such as frustration or a loss of trust in the medical system or doctors.
Example: A person takes a placebo for pain relief, and when they realize there was no real treatment, they feel disappointed or angry.
Worsening Symptoms or Unforeseen Reactions
Description: Sometimes, the placebo can cause unexpected reactions, especially if the patient is taking other medications or has specific medical conditions.
Harms: The placebo might worsen symptoms or interact negatively with other medications the patient is taking.
Example: A person taking other medications for health conditions uses a placebo at the same time, which might cause harmful reactions or unwanted effects.
Hindering Scientific Progress in Medicine
Description: The use of a placebo in research and clinical trials could lead to inaccurate results or misleading assessments of the effectiveness of real medications and treatments.
Harms: The placebo could impact clinical study results or medical research, leading to incorrect or misleading outcomes.
Example: If a placebo is used in a study to assess a medication's effectiveness, the results might be inaccurate if the placebo effects are similar to those of the real medication.
Violation of Legal Rights of the Patient
Description: In some cases, using a placebo without informing the patient could be considered a violation of their legal and ethical rights.
Harms: Doctors or hospitals could face legal issues if it is found that a placebo was used without the patient's consent or without making them aware.
Example: If a placebo is administered to a patient without their knowledge or consent, it could be seen as a violation of their legal right to appropriate treatment and informed consent.
Uses of Placebo
Placebo is used in many cases and for different groups of people, but generally, it is used in scientific research and among specific groups that benefit from placebo treatments:
Scientific Research (Clinical Trials)
Description: In clinical trials and medical research, placebos are used as a "comparison" to see the effects of real medications. Some participants receive real medication, while others are given a placebo to compare the effect of actual treatment with the psychological impact caused by expectations.
Beneficiary Group: Patients participating in clinical trials, where placebos are used to differentiate between the effects of real treatment and psychological effects.
Patients with Chronic Diseases
Description: Sometimes, placebos are used to treat symptoms associated with chronic diseases such as chronic pain, anxiety, or psychological symptoms.
Beneficiary Group: Patients with chronic conditions that require ongoing treatment. The placebo can temporarily improve symptoms through the power of the mind.
Patients with No Effective Treatment Available
Description: When no effective medical treatment exists for a condition, doctors may sometimes prescribe a placebo to improve a patient's psychological or physical symptoms.
Beneficiary Group: Patients suffering from conditions or symptoms for which there is no clear or effective treatment, such as certain mental disorders or pain with an unclear cause.
Patients with Psychological Disorders
Description: Placebo is sometimes used as a treatment to alleviate psychological symptoms such as anxiety or depression, especially when patients do not respond to traditional treatments.
Beneficiary Group: People suffering from psychological disorders like depression or anxiety, where positive expectations help improve their mental state.
Children and Elderly
Description: Placebo is sometimes used with children or the elderly, particularly when there is no effective treatment available, or when medical treatment is not suitable due to sensitivity or health conditions.
Beneficiary Group: Children, in some cases like mild pains or sleep disorders, and the elderly, especially for chronic diseases or pain.
Patients Needing Psychological Support
Description: Sometimes, doctors may use a placebo to provide psychological support to those suffering from unexplained symptoms or requiring significant moral support.
Beneficiary Group: People who suffer from psychological conditions that can significantly improve if they believe in their improvement, even if the treatment is not scientifically effective.
People Suffering from Unexplained Physical Pain
Description: Individuals suffering from unexplained pain (such as joint or muscle pain) who cannot find effective treatment may benefit from placebo.
Beneficiary Group: People with chronic pain or unexplained pain, as placebo can help alleviate the pain due to its psychological impact on the mind.
Patients Undergoing Complementary or Alternative Treatments
Description: Placebo is also used in some alternative or complementary therapies, such as herbal treatments, energy healing, etc., to make the person believe that this treatment will benefit them.
Beneficiary Group: People following alternative or complementary treatments like herbal remedies, who believe these treatments will improve their health.
Patients Suffering from Stress or Insomnia
Description: In some cases, placebo is used to improve sleep or relieve stress indirectly, especially when no effective treatment is available.
Beneficiary Group: People suffering from insomnia or sleep disorders, as positive expectations help them sleep better.
Patients in Advanced Stages of Illness
Description: In cases of advanced illness or cancer, placebo can be used to improve quality of life by alleviating symptoms like pain or stress.
Beneficiary Group: Cancer patients or those with severe illnesses in advanced stages, where placebo may reduce symptoms or improve mood even though there is no real medical effect.
Doctors who use placebos are often specialists in one of the following fields:
Psychiatrists
Specialization: Psychiatrists use placebos in some psychological conditions like anxiety, depression, and sleep disorders. The placebo effect in this field largely depends on the patient’s psychological expectations.
Pain Specialists
Specialization: Sometimes, pain specialists use placebos to treat conditions that do not respond to conventional treatments. This may include chronic pain or pains that do not have a clear medical explanation.
Internists
Specialization: In cases of chronic diseases with no effective treatment or when the symptoms are not fully explained, internists may sometimes use placebos to alleviate psychological or physical symptoms.
Complementary and Alternative Medicine Specialists
Specialization: Some doctors specializing in complementary and alternative medicine use placebos as part of their therapeutic strategies, especially in treating conditions that require psychological or moral support.
Clinical Trial Researchers
Specialization: Researchers in clinical trials use placebos to assess the effectiveness of new drugs. They are not always treating doctors, but they play a significant role in determining the placebo effect on patients in research settings.